The Colombo IOL (Moptim, Shenzhen, China) is an emerging instrument that employs SD-OCT technology for the measurement of ocular biological parameters, including AL, central corneal thickness (CCT), anterior chamber depth (ACD), lens thickness (LT), keratometry (K), white-to-white (WTW) distance, and pupil diameter (PD). The assessment of these indicators bears significant clinical implications. For instance, AL, CCT, K1, and K2 can be utilized to identify biomarkers associated with conditions such as keratoconus and pathological fundus changes associated with high myopia6. Currently, the available instruments for obtaining these data also encompass Swept Source OCT (IOLMaster 700, Carl Zeiss Meditec, Germany) or OLCR Biometer (SW9000, Suoer, Tianjin, China).

Despite the prevalent use of optical biometers, there is a notable gap in studies that specifically evaluate the SD-OCT biometer of the Colombo IOL. A recent publication has assessed the agreement of ocular parameters in adult patients with myopia between the Colombo IOL and the IOLmaster 7007, while limited research on children’s cases is available in current literature. Furthermore, the accuracy of the Colombo IOL has not been simultaneously compared with OLCR instruments (SW-9000). Consequently, the main objective of this study is to evaluate the accuracy of the Colombo IOL and establish its agreement with the IOLMaster 700 and SW-9000 in measuring essential parameters such as AL, CCT, K1, and K2 in healthy pediatric population.